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Treatment-Resistant Depression Care in Westmoreland County
Depression that has not improved with other antidepressants, treated in Export, PA with medication changes and Spravato (esketamine).
Reviewed by Christin Bell, PA-C. Last reviewed October 26, 2026.
Tranquil Tides Psychiatry treats treatment-resistant depression for adults in Export, PA. This is depression that has not improved after trying other antidepressant medications. It has its own options, including Spravato (esketamine), beyond what has already been tried.
Treatment-resistant depression is a recognized diagnosis with its own treatment options, and several medications failing does not close those options off.
Your first visit is a conversation about what you have already tried, what helped, what did not, and what side effects you noticed along the way. If parts of that are frustrating or discouraging to go back over, you can say so. Your provider goes over your full history before talking through the options with you.
One option is Spravato (esketamine), an FDA-approved prescription nasal spray, given and monitored in our office, on its own or together with an oral antidepressant. You and your provider decide together whether Spravato fits your history. Other medication adjustments, including changes to what you are already taking or trying a different combination, are also part of the conversation.
Care continues with follow-up visits that track how things are going, what side effects you are noticing, and what needs to change. Follow-up visits are typically more frequent at the start of a new treatment and less often once things settle. If ongoing therapy or counseling would help alongside psychiatric care, your provider will point you toward the right professional.
How we treat it
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Treatment-Resistant Depression: common questions
What does treatment-resistant depression mean?
Treatment-resistant depression means depression that has not improved after trying other antidepressant medications. Spravato (esketamine) and further medication changes are among the treatments for it.
Is Spravato the only option for treatment-resistant depression?
No. Spravato (esketamine) is one option. Your provider also reviews other medication changes with you, and the two of you decide together what makes sense based on your history.
How do I know if Spravato is right for me?
Your provider goes over your history and what you have already tried, then talks through whether Spravato is a reasonable option. Not everyone is a candidate.
Do I need to see a psychiatrist to be considered for treatment-resistant depression care?
You need an evaluation with your provider first. That conversation is what determines whether treatment-resistant depression describes your situation and what the options are.
Next step
Talk to us about treatment-resistant depression
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